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(A) Lolliplots showing distribution of somatic mutations in TP53 in 263 patients undergoing resection of colorectal liver metastases. (B) Overall survival by type of TP53 mutation (n = 399). Two patients with TP53 in-frame deletions were omitted from analysis. (C) Overall survival among RAS mutated patients, by type of TP53 mutation (n = 209). EAp53, Evolutionary Action of p53; W, TP53 wild-type; T/L, truncating or EAp53 low risk mutation; H, EAp53 high risk mutation; mut, mutation.
