Table 1.
Baseline Characteristics of Enrolled Patients
| Characteristic | Placebo (N = 78) | BCG (N = 72) | p value |
|---|---|---|---|
| Age, years, mean (SD) | 79.6 (7.8) | 79.9 (7.6) | 0.802 |
| Male gender, no. (%) | 35 (44.9) | 32 (44.4) | 1.000 |
| Charlson’s Comorbidity Index, mean (SD) | 5.5 (1.9) | 5.5 (2.2) | 0.909 |
| ΑPACHE II score on study enrolment, mean (SD) | 7.9 (3.0) | 8.1 (2.9) | 0.701 |
| SOFA score on study enrolment, mean (SD) | 1.2 (1.4) | 1.0 (1.1) | 0.586 |
| Comorbidities, no. (%) | |||
| Diabetes mellitus, no. (%) | 29 (37.2) | 23 (31.9) | 0.607 |
| Without organ damage, no. (%) | 23 (29.5) | 15 (20.9) | 0.262 |
| With organ damage, no. (%) | 6 (7.7) | 8 (11.1) | 0.578 |
| Chronic heart failure, no. (%) | 23 (29.5) | 20 (27.8) | 0.858 |
| Chronic renal disease, no. (%) | 14 (17.9) | 12 (16.7) | 1.000 |
| Chronic obstructive pulmonary disease, no. (%) | 12 (15.4) | 11 (15.3) | 1.000 |
| Cerebrovascular disease, no. (%) | 17 (21.8) | 21 (29.2) | 0.349 |
| Degenerative disease, no. (%) | 8 (10.3) | 6 (8.3) | 0.783 |
| Myocardial infarction, no. (%) | 13 (16.7) | 9 (12.5) | 0.498 |
| Biliary stones, no. (%) | 10 (12.8) | 11 (15.3) | 0.814 |
| Renal stones, no. (%) | 1 (1.3) | 1 (1.4) | 1.000 |
| Any surgery, no. (%) | 30 (38.5) | 30 (41.7) | 0.740 |
| Dementia, no. (%) | 15 (19.2) | 20 (27.8) | 0.249 |
| Hemiplegia, no. (%) | 1 (1.3) | 1 (1.4) | 1.000 |
| Peptic ulcer disease, no. (%) | 3 (3.8) | 3 (4.2) | 1.000 |
| Peripheral vascular disease, no. (%) | 1 (1.3) | 0 (0) | 1.000 |
| Liver disease, no. (%) | 1 (1.3) | 1 (1.4) | 1.000 |
| Hypertension, no. (%) | 56 (71.8) | 53 (73.6) | 0.856 |
| Atrial fibrillation, no. (%) | 30 (38.5) | 22 (30.6) | 0.391 |
APACHE, acute physiology and chronic health evaluation; SD, standard deviation; SOFA, sequential organ failure assessment.