Table 3.
ANOVA of calculated model for responses
| Result of the analysis of variance | Particle size (nm) | Entrapment efficiency (%) |
Drug loading
(%) |
|---|---|---|---|
| Regression | |||
| Sum of squares | 13029.42 | 2348.04 | 157.64 |
| Degrees of freedom (df) | 9 | 9 | 9 |
| Mean squares | 1447.71 | 260.89 | 17.52 |
| F-value | 102.64 | 144.65 | 754.55 |
| P | <0.0001 | <0.0001 | <0.0001 |
| Lack of fit tests | |||
| Sum of squares | 89.63 | 12.31 | 0.13 |
| Degrees of freedom (df) | 3 | 3 | 3 |
| Mean squares | 29.88 | 4.10 | 0.044 |
| F-value | 13.13 | 51.72 | 5.77 |
| P | 0.0154 | 0.0012 | 0.0618 |
| R2 | 0.9925 | 0.9947 | 0.9990 |
| Correlation of variation (CV%) | 2.29 | 3.07 | 1.40 |