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Metabolism probabilities pathway for synthesized (5a, b and g) compounds
| Compound |
Substrate
|
Inhibitor
|
||||||
|---|---|---|---|---|---|---|---|---|
| CYP450 2C9 | CYP450 2D6 | CYP450 3A4 | CYP450 2C9 | CYP450 2D6 | CYP450 3A4 | CYP450 1A2 | CYP450 2C19 | |
| SB202190 | - | - | - | + | + | + | + | + |
| 5a | - | - | + | - | - | - | + | - |
| 5b | - | - | - | - | - | - | + | + |
| 5g | - | - | - | + | - | - | + | + |
