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Components of each transdermal patch
| Formulation |
Succinic Acid
(mg) |
Citroflex
(µL) |
Eudragit
®
E100
(mg) |
PVP K30
(mg) |
Losartan Potassium
(mg) |
Methanol
(mL) |
|---|---|---|---|---|---|---|
| F1 | 0 | 800 | 1000 | 1000 | 1000 | 25 |
| F2 | 300 | 800 | 1000 | 1000 | 1000 | 25 |
| F3 | 300 | 750 | 1000 | 1000 | 1000 | 25 |
| F4 | 0 | 700 | 1000 | 1000 | 1000 | 25 |
| F5 | 0 | 750 | 1000 | 1000 | 1000 | 25 |
| F6 | 300 | 700 | 1000 | 1000 | 1000 | 25 |
| Optimal | 300 | 765 | 1000 | 1000 | 1000 | 25 |
