Figure 3.

Changes in [Ca²⁺]i levels induced by chemical OGD (4 mM NaN₃) in the presence of 2 µM noscapine in primary cortical neurons. (A) Time course of NaN₃-induced [Ca²⁺]i rise in presence of 2 µM noscapine. NaN₃ (4 mM) stimulated [Ca²⁺]i levels increase. After 30 min ischemic insult, the cells were treated with 2 µM noscapine during chemical ischemia. Two micromolar noscapine could decrease [Ca²⁺]i levels during chemical ischemia. (B) Bar graph of mean change in [Ca²⁺]_i levels acquired in response to chemical ischemia in presence of 2 µM noscapine. ^***P < 0.001 vs. NaN3 group