Table 3.
Detection of SARS-CoV-2 nucleic acids in confirmed mother–infant pairs in early 2020
| Characteristic | Pair no. |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | |
| Delivery date | 19 Jan | 22 Jan | 24 Jan | 30 Jan | 31 Jan | 31 Jan | 3 Feb | 5 Feb | 9 Feb | 9 Feb | 20 Feb | 29 Feb | 5 Mar | 16 Mar |
| Gestational age at delivery (weeks) | 36+4 | 38+4 | 38+1 | 36+5 | 37 | 38+2 | 40+5 | 38+4 | 39+1 | 39 | 41+1 | 39 | 38 | 39+5 |
| Caesarean section | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | No | Yes | Yes | Yes | Yes | No |
| Maternal SARS-CoV-2 nucleic acid detection | ||||||||||||||
| Positive throat swab date | 31 Jan | 5 Feb | 28 Jan | 8 Feb | 31 Jan | 31 Jan | 6 Feb | 5 Feb | 10 Feb | 9 Feb | NA | NA | 2 Feb | 4 Feb |
| Negative throat swab date 1 | 18 Feb | 17 Feb | 31 Jan | 9 Feb | 8 Feb | 22 Feb | 9 Feb | 13 Feb | 21 Feb | 12 Feb | 17 Feb | 3 Feb | 12 Feb | 12 Feb |
| Negative throat swab date 2 | 22 Feb | 19 Feb | NA | 11 Feb | 13 Feb | 24 Feb | NA | 16 Feb | 24 Feb | 14 Feb | 19 Feb | 1 Mar | 4 Mar | 14 Feb |
| SARS-CoV-2 shedding time (days) | 18 | 12 | 3 | 1 | 8 | 22 | 3 | 8 | 11 | 3 | NA | NA | 10 | 8 |
| Breast milk (n = 12) | NA | NA | — | — | — | — | — | — | — | — | — | — | — | — |
| Vaginal secretion (n = 10) | NA | NA | NA | — | NA | — | — | — | — | — | — | — | — | — |
| Anal swab (n = 12) | NA | — | NA | — | — | — | — | — | — | — | — | — | — | — |
| Neonatal SARS-CoV-2 nucleic acids detection | ||||||||||||||
| Throat swab (n = 12) | — | — | NA | — | NA | — | — | — | — | — | — | — | — | — |
| Meconium (n = 6) | NA | NA | NA | NA | NA | NA | NA | — | — | — | — | — | — | NA |
Maternal negative throat swab dates were presented as two continuous dates separated by at least 48 hours. SARS-CoV-2 shedding time was counted as duration from first positive date to first consecutive negative date. Disease of mothers 11 and 12 was confirmed by epidemiologic exposure, characteristic symptoms and positive SARS-CoV-2 combined IgM/IgG tests; their throat swab results remained negative two separate times.
Dash indicates negative results. COVID-19, coronavirus disease 2019; NA, not available; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.