Table 5.
Details of studies with hydroxychloroquine and no control group (Single arm studies).
| Study | Type of Study | Total patients | Favourable outcome | Dose of Hydroxychloroquine | Azithromycin | Outcome measured |
|---|---|---|---|---|---|---|
| Gautret et al. | Prospective Observational | 80 | 65 (81.25%) | Hydroxychloroquine 200 mg thrice daily for 10 days | Yes | Viral Load at Day 7 Viral Cultures at Day 5 Chest CT |
| Molina et al. | Prospective Observational | 11 | 0 (0%) | Hydroxychloroquine 600 mg/d for 10 days | Yes | Qualitative PCR of nasopharyngeal swab |
| Million et al. | Retrospective | 1061 | 973 (91.7%) | Hydroxychloroquine 200 mg thrice daily for 10 days | Yes | Death, clinical worsening (transfer to ICU, and >10 day hospitalization), viral shedding persistence (>10 days) |