Table 1. Inhaled asthma controller medications available in Brazil.a.
| Inhaled corticosteroid alone | ||||
|---|---|---|---|---|
| Medications | Inhaler (number of doses) | Trade name® | Dose administered | Age approved in the insert |
| BDP (HFA)b | pMDI (200) | Clenil spray | 50 µg | Children and adults |
| 200 or 250 µg | Only adults | |||
| BDP | DPI capsules (60) | Miflasona | 200 or 400 µg | Children and adults |
| BUD | DPI capsules (15 and 60) | Busonide caps | 200 or 400 µg | ≥ 6 years |
| Aerolizer (30 and 60) | Miflonide | |||
| FTC | Diskus (60) | Flixotide | 50 or 250 µg | ≥ 4 years |
| FTC (HFA) | pMDI (60 or 120) | Flixotide spray | 50 µg | ≥ 1 year |
| 250 µg | ≥ 4 years | |||
| MOM | DPI - Capsules (60) | Oximax | 200 or 400 µg | ≥ 12 years |
| Inhaled corticosteroids in combination with LABA | ||||
| Medications | Inhaler (number of doses) | Trade name® | Dose administered | Age approved in the insert |
| FORM + BUD - | Aerocaps single capsule (15/30/60) | Alenia | 6/100 µg or 6/200 µg | ≥ 4 years |
| 12/400 µg | ≥ 6 years | |||
| FORM + BUD - | Aerolizer separate capsules (60) | Foraseq | 6/100 µg or 6/200 µg | ≥ 12 years |
| FORM + BUD - | Turbuhaler (60) | Symbicort Turbuhaler | 6/100 µg or 6/200 µg | ≥ 4 years |
| 12/400 µg | ≥ 12 years | |||
| FORM + BUD (HFA) - | pMDI (120) | Symbicort; Vannair spray | 6/100 µg | ≥ 6 years |
| 6/200 µg | ≥ 12 years | |||
| FORM + BDP (HFA)b | pMDI (120) | Fostair spray | 6/100 µg | ≥ 18 years |
| FORM + BDPb | Next (120) | Fostair DPI | 6/100 µg | ≥ 18 years |
| FORM + FP | CDM-Haller single capsule (60) | Lugano | 12/250 µg | ≥ 12 years |
| SALM + FP (HFA) | Diskus (60) | Seretide Diskus | 50/100 µg | ≥ 4 years |
| 50/200 µg or 50/500 µg | ≥ 12 years | |||
| SALM + FP (HFA) | pMDI (120) | Seretide spray | 25/50 µg | ≥ 4 years |
| 25/125 µg or 25/250 µg | ≥ 12 years | |||
| Inhaled corticosteroid in combination with a SABA | ||||
| Medications | Inhaler (number of doses) | Trade name® | Dose administered | Age approved in the insert |
| BDP (HFA) | pMDI (200) | Clenil Compositum HFA | 50/100 µg | ≥ 6 years |
| Solution for nebulization | Clenil Compositum A | 400 µg g/mL and 800 µg/mL | Children and adults | |
| Inhaled corticosteroid in combination with an ultra-LABA | ||||
| Medications | Inhaler (number of doses) | Trade name® | Dose administered | Age approved in the insert |
| FF + VI | Ellipta (30) | Relvar | 100/25 µg or 200/25 µg | ≥ 12 years |
| LAMA | ||||
| Medications | Inhaler (number of doses) | Trade name® | Dose administered | Age approved in the insert |
| Tiotropium (AC) | Respimat (60) | Spiriva | 2.5 µg | ≥ 6 years |
BDP: beclomethasone dipropionate; HFA: hydrofluoroalkane; pMDI: pressurized metered-dose inhaler; DPI: dry powder inhaler; BUD: budesonide; FP: fluticasone propionate; MOM: mometasone furoate; LABA: long-acting β2 agonist; FORM: formoterol fumarate; SALM: salmeterol xinafoate; SABA: short-acting β2 agonist; FF: fluticasone furoate; VI: vilanterol; LAMA: long-acting muscarinic antagonist; and AC: aerosol “cloud”. aThe recommendations for each dose of medication were taken from the package inserts of medications approved by the Brazilian National Health Oversight Agency. The equivalence of medications in this table and ages with evidence for clinical use should be verified. bExtra fine particles.