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. 2020 Jul 30;23(4):385–397. doi: 10.4048/jbc.2020.23.e42

Table 5. Expression of EMPs, histological grade, and proliferative index on the basis of HER2 status.

Characteristics EMP1 EMP2 EMP3
Positive Negative p-value Positive Negative p-value Positive Negative p-value
HER2 negative (n = 345)
Histologic grade 0.285 < 0.001 0.652
I (n = 70) 66 (94.3) 4 (5.7) 56 (80.0) 14 (20.0) 58 (82.9) 12 (17.1)
II (n = 150) 147 (98.0) 3 (2.0) 116 (77.3) 34 (22.7) 125 (83.3) 25 (16.7)
III (n = 125) 122 (97.6) 3 (2.4) 70 (56.0) 55 (44.0) 99 (79.2) 26 (20.8)
Ki67 LI (%) 18.74 ± 21.16 17.70 ± 18.01 0.877 16.11 ± 19.59 24.79 ± 23.09 0.001 18.22 ± 20.71 20.90 ± 22.55 0.361
HER2 positive (n = 73)
Histologic grade NA 0.504 0.851
I (n = 6) 6 (100.0) 0 (0.0) 5 (83.3) 1 (16.7) 6 (100.0) 0 (0.0)
II (n = 41) 41 (100.0) 0 (0.0) 36 (87.8) 5 (12.2) 39 (5.1) 2 (4.9)
III (n = 26) 26 (100.0) 0 (0.0) 20 (76.9) 6 (23.1) 25 (96.2) 1 (3.8)
Ki67 LI (%) 15.15 ± 11.23 NA NA 15.90 ± 11.53 11.42 ± 9.05 0.209 15.45 ± 11.37 8.33 ± 2.89 0.286

Values are presented as number (%) or mean ± standard deviation.

EMP = epithelial membrane protein; HER2 = human epidermal growth factor receptor 2; LI = labelling index; NA = not available.