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. 2020 Sep 1;10:14351. doi: 10.1038/s41598-020-71264-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Enriched GO network related to KEGG pathways (https://www.kegg.jp/kegg/pathway.html) in (A) left ventricle myocardium of rats and (B) right ventricle myocardium of rats in end-stage monocrotaline-induced PAH. (C) KEGG pathways significantly enriched in right ventricle myocardium of rats with end-stage PAH depicted as a circle chart (p < 0.05). Biological processes and genes shared between pathways in left/right ventricle were visualized with ClueGO (kappa score ≥ 0.4) under the Cytoscape 3.3.0 environment as a functional grouped network. Each node represents a GO term or a gene. The enrichment significance of the GO terms is reflected by the size of the nodes. Edges represent connections between the nodes. (ClueGO under the Cytoscape 3.3.0 environment, https://apps.cytoscape.org/apps/cluego).