Table 2.

Serum parameters for fluoride (F) and calcium metabolism at the time of sacrifice

Parameter	Sham	Sham + F	Nephrectomy	Nephrectomy + F
Number	10	10	10	9
Fluoride (μM)	0.79 ± 0.31	1.72 ± 1.01	1.08 ± 0.31	3.71 ± 1.47a,b,c
Ionized calcium (mmol/l)	1.07 ± 0.31	1.23 ± 0.27	0.93 ± 0.34	1.22 ± 0.15c
Total calcium (mg/dl)	9.0 ± 1.0	11.6 ± 1.2a,c	9.8 ± 0.6	9.7 ± 1.5b
Phosphorus (mg/dl)	5.9 ± 0.6	7.5 ± 1.8	5.8 ± 1.1	9.4 ± 2.6b,c
Alkaline phosphatase (IU/l)	167 ± 43	223 ± 54	337 ± 78a,b	315 ± 60a,b

Values are mean ± standard deviation

^a Significantly different from sham

^b Significantly different from sham+F

^c Significantly different from nephrectomy