Fig. 2.

Transcriptional regulation of SGLT1/Sglt1. Response elements in the promotor of human SGLT1 and components that were shown to be involved in transcriptional regulation of SGLT1/Sglt1 are indicated. Components that participate in transcriptional regulation in the small intestine are marked with yellow. If they participate in d-glucose-dependent regulation, they are indicated in red. EGFR, epithelial growth factor receptor; Rg1, ginsenoside component Rg1; SGK, serum- and corticoid-stimulated kinase; CREB, cAMP response element- binding protein- ; CBP, cAMP response element protein–binding protein; PER1, period circadian regulator 1; BMAL1, brain and muscle ANRT-like 1; SP1-1, specificity protein 1 subtype 1; HNF1, hepatic nuclear factor 1