Fig. 3.

Membrane trafficking of SGLT1/Sglt1. The scheme is based on experiments in which SGLT1 from human or rabbit was expressed in oocytes, and on experiments with mouse small intestine. Components which have been shown to be involved in short-term regulation of SGLT1/Sglt1 in the small intestine are indicated in yellow. The proteasomal degradation pathway is not well explored. RELM, resistin-like molecule; HSP, heat shock protein; TGF, tissue growth factor; JAK, Janus-activated kinase; AMPK, AMP-activated protein kinase; CamK, calmodulin-stimulated kinase; ODC, ornithine decarboxylase; NEDD, neural precursor cell expressed developmentally downregulated; SGK, serum- and glucocorticoid-stimulated kinase