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Model depicting the presumed role of RS1 in d-glucose-dependent release of vesicles containing human SGLT1 from the Golgi (a, b) and the action of modified peptides derived from RS1-Reg (c) that downregulate SGLT1 in the BBM. RS1-Reg in RS1 is indicated in gray. TGN, trans-Golgi network; ODC, ornithine decarboxylase; BP, putrescine-binding protein of a budding protein complex that induces the release of vesicles containing human SGLT1 from the TGN
