Table 2.

Description of the studies reported in this review in which regulations of monosaccharide transporters were investigated that are supposed to be relevant for absorption of d-glucose, d-galactose, and d-fructose in human small intestine

Level of regulation	GLUT2/Glut2	GLUT5/Glut5	SGLT1/Sglt1
Transcription	Human: e.c.c.; rodents: in vivo	Human: e.c.c., C; rodents: in vivo	Human: e.c.c., C; pig: L; sheep: in vivo; rabbit: e.c.c.; rodents: in vivo
mRNA stability		Human: C	Pig: L
Translation or protein stability	Rodents: in vivo (n.d.)	Rodents: in vivo (n.d.)	Sheep: in vivo (n.d.); rabbit: e.o. (p.s.)
Protein trafficking	Rodents: in vivo		Human: e.o.; rabbit: e.o.; rodents: in vivo

Different levels of regulation were investigated in different species in vivo and in vitro. For in vitro studies, two cell models and different expression systems were employed

C, measurements in Caco2 cells derived from human; L, measurements in LLCP-K1 cells derived from pig; e.o., transporter expression in oocytes of Xenopus laevis; e.c.c., transporter expression in cultivated cells; n.d., no differentiation between translation and protein stability was performed; p.s., protein stability was investigated