Table 1.
Apparent Km values [mM] of trans-zero d-glucose uptake by human glucose transporters that are expressed in brain
Transporter | d-Glucose | d-Galactose | d-Fructose | 2-Deoxy-glucose | 3-O-Methyl-glucose | Reference |
---|---|---|---|---|---|---|
GLUT1 | 0.7–3.2 | tr. | no tr. | 6.9 | 1.4 | [49, 362, 438, 439, 442] |
GLUT2 | 17–20 | 86 | 67 | 11, 17 | 17 | [49, 72, 144, 193, 407] |
GLUT3 | ~ 1.5 | 8.5 | no tr. | 1.4, 1.8 | 10.6 | [49, 72, 143, 144, 400] |
GLUT4 | 12.6 | tr. | no tr. | 4.6 | 4.3 | [49, 297, 439, 442] |
GLUT5 | not t. for tr. | not te. | 6 | tr. | not te. | [50, 198, 203] |
GLUT6 | tr. | not te. | not te. | tr. | not te. | [53, 103] |
GLUT8 | tr. | i., not te. for tr. | i., not te. for tr. | 2.4 | not te. | [104, 178] |
SGLT1 | 0.5 | 1 | no tr. | > 100 | > 100 | [446] |
SGLT2 | 5 | > 100 | > 100. | not te. | not te. | [446] |
tr. transport, no tr. no transport, i. inhibition, not te. for tr. not tested for transport, not te. not tested