Table 8.
Patents related to the application of PVP in Pharmaceuticals.
| Patent No. | Title/ | Assignee | Inventor(s) | Patent/Publication Date | PVP grade used | Purpose |
|---|---|---|---|---|---|---|
| US 10406105B2 | Pharmaceutical formulation for the production of rapidly disintegrating tablets | BASF SE (Ludwigshafen, DE) | Karl K, Michael S, Silke G, Kathrin MB, Angelika M. |
10-09-2019 | Kollidon CL-SF | Super disintegrant |
| Kollidon 30 | Binder | |||||
| Kollidon VA 64 | Binder | |||||
| Kollicoat SR 30 D | Dispersing agent | |||||
| EP 2001450B1 | Directly compressible composite for orally disintegrating tablets | Rubicon Research Private Limited (Mumbai, IN) | Pilgaonkar PS, Rustomjee MT, Gandhi AS, Bagde P, Morvekar HN. |
30-01-2019 | Crospovidone | Disintegrant |
| US 20180036245A1 | Solid dispersions | Shionogi Inc. (Florham Park, NJ, US) | Zhengming C, Xiaoming C, Kevin H. |
08-02-2018 | Kollidon 30 (PVP K30), Kollidon VA64 (PVP VA 64) |
Hydrophilic carriers |
| WO 2018102526A1 | Pharmaceutical dosage form | Glaxosmithkline LLC (Wilmington, DE, US) | Burke MD, Goodwin D, Govindarajan R, Harridance A, Kedia S, Le Q, Mcaleese P, Westrup J. |
07-06-2018 | Povidone, Copovidone | Solubilizing agents |
| Crospovidone | Disintegrant | |||||
| US 9623010B2 | Orodispersible tablets | Laboratorios Lesvi, S.L. (Barcelona, ES) | Carmen UP, Ignacio DM, Pablo PA. |
18-04-2017 | Crospovidone | Disintegrant |
| US 20170224624A1 | Formulations of enzalutamide | Bend Research, Inc. (Bend, OR, US), Medivation Prostate Therapeutics, Inc. (San Francisco, CA, US), Astellas Pharma Inc. (Tokyo JP) |
Douglas AL, Sanjay K, Randy JW, Jason AE, Sheila M, Yuuki T, Toshiro S, Ryousuke I, Shinsuke O, Hiroyasu T, Koji N, Atsushi K. |
10-08-2017 | Povidone, Copovidone | Solubilizing agents |
| EP 2283824B1 | Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin | Special Product's Line S.p.A. (Pomezia, IT), So. Se. Pharm S.r.l. (Pomezia, IT) |
Camponeschi C, Colombo P |
19-04-2017 | PVP K30 | Binder |
| US 9629841B2 | Formulations of pyrimidinedione derivative compounds | AbbVie Inc. (North Chicago, IL, US) | Yanxia L, Ping G, Yi S, Geoff GZ, Yi G, Jianwei W |
25-04-2017 | Kollidon VA 64, Kollidon VA 64 fine | Stabilizing polymer, Bioavailability enhancer |
| US 20160101103A1 | Method for the production of a medicament containing tadalafil | Ratiopharm GmbH. (Ulm, DE) | Rainer A, Julia SN, Katrin R. |
14-04-2016 | Copovidone | Solid solvent |
| US 9308164B2 | Hyoscyamine dosage form | Sovereign Pharmaceuticals, LLC. (Fort Worth, TX, US) |
Viswanathan S, Ralph B, David B, Himanshu P, Juan CM, Somphet PS |
12-04-2016 | Kollidon SR | Sustained release polymer |
| US 20160193153A1 | Tablet comprising crospovidone | DSM Sinochem Pharmaceuticals (Netherlands B.V., Delft, NL) | Abraham CL | 07-07-2016 | Crospovidone | Disintegrant |
| US 20160000732A1 | Oral pharmaceutical compositions of ospemifene | Cadila Healthcare Limited (Ahmedabad, IN) | Sushrut KK, Pavak RM, Ritesh K |
07-01-2016 | Crospovidone | Disintegrant |
| US 20150011525A1 | Solid dispersion of poorly soluble compounds comprising crospovidone and at least one water-soluble polymer | ISP Investments Inc. (Wilmington, NJ, US) | Yunxia B, Mohammed AR, James DL |
08-01-2015 | Crospovidone | Disintegrant, Bioavailability enhance, Crystallization inhibitor |
| US 8945620B2 | Solid pharmaceutical compositions containing pregabalin | Warner-Lambert Company LLC. (New York, NY, US) |
Howard NB, Yun HC, Steven DS, Majid M, Thomas DR, Pushpa GS, Zezhi JS, Jiansheng W |
03-02-2015 | Kollidon SR | Matrix forming agent, Swelling agent, Sustained release polymer |
| WO 2015107536A2 | Fixed dose combination comprising linagliptin and metformin HCl | Intas Pharmaceuticals Limited (Gujarat, IN) | Priyank P, Mayur P, Mahendra P, Ashish S |
23-07-2015 | Copovidone | Binder |
| US 8691878B2 | Solid pharmaceutical dosage form | AbbVie Inc. (North Chicago, IL, US) | Jeorg R, Ulrich R, Bernd L, Gunther B, Joerg B, Laman A, Soumojeet G. |
08-04-2014 | Copovidone | Bioavailability enhancer |
| US 8691872B2 | Dispersions of rasagiline citrate | Teva Pharmaceutical Industries Ltd. (Petach-Tikva, IL) | Keith L, David E. |
08-04-2014 | PVP K29/32, PVP K90, PVP VA | Solubilizer |
| US 20140221414A1 | Solid dispersion of rifaximin | Lupin Limited (Mumbai, IN) | Shirishkumar K, Satish KD, Harshal AJ. |
07-08-2014 | Povidone, Copovidone | Solubilizing agents, Hydrophilic carriers |
| US 8920837B2 | Sustained release dosage form | Rubicon Research Private Limited (Mumbai, IN) | Pratibha SP, Maharukh TR, Anilkumar SG, Paras RJ, Atul AK. |
30-12-2014 | Kollidon SR | Sustained release polymer |
| Kollidon VA 64 | Binder | |||||
| US 8715729B2 | Rapidly disintegrating, solid coated dosage form | BASF SE (Ludwigshafen, DE) | Karl K, Silke G, Yoshitaka K. |
06-05-2014 | Kollidon CL-SF | Super disintegrant |
| US 8568780B2 | Pharmaceutical formulation for the production of rapidly disintegrating tablets | BASF SE (Ludwigshafen, DE) | Karl K, Michael S, Silke G, Kathrin MB, Angelika M. |
29-10-2013 | Kollidon CL-SF | Disintegrant |
| US 20110262533A1 | Pharmaceutical formulation for use in HIV therapy | – | Kiran KNV, Sanjay DV, Akhilesh AD, Abhijit MD, Sanjeev MS |
05-02-2013 | Copovidone | Binder |
| WO 2013040187A1 | Solid dispersion of poorly soluble compounds comprising crospovidone and at least one water-soluble polymer | ISP Investments Inc. (Wilmington, DE, US) | Yunxia BL, Rahman MA, Lester JD. |
21-03-2013 | Crospovidone | Disintegrant |
| US 8574625B2 | Tablet dosage form | Wockhardt Ltd. (Bandra East, Mumbai, IN) | Girish KJ, Ramakant G, Rahul D. |
05-11-2013 | Crospovidone | Disintegrant |
| US 20110028456A1 | Solid pharmaceutical dosage form | Cipla Limited (Mumbai, IN) | Amar L, Geena M. |
03-02-2011 | Kollidon VA 64 | Dissolution enhancer |
| WO 2011125075A2 | A novel gastroretentive delivery of macrolide | FDP Limited (Mumbai, IN) | Chandavarkar NM, Jindal KC, Malayandi R. |
13-10-2011 | Crospovidone | Swelling agent, Hydrophilic polymer |
| US 7838033B2 | Composition for rapid disintegrating tablet in oral cavity | Fuji Chemical Industry Co. Ltd. (Nakaniikawa-gun, JP) | Nobukazu T, Yoshiro N, Hiroshi K, Tadashi F, Terumasa H. |
23-11-2010 | Crospovidone | Disintegrant |