Table 2.
Characteristics of the breast cancer-free female cohort.
| Demographics and clinical characteristics | Breast cancer-free female cohort, N = 36,146 (% or ± SD) |
|---|---|
| Age (years) | 51.09 ± 15.35 |
| Age at menarche (years) | 12.82 ± 1.51 |
| Age at first live birth (nulliparous excluded, years) | 24.10 ± 5.03 |
| Parity (nulliparous excluded) | 1.92 ± 1.32 |
| Age at menopause (premenopausal women excluded, years) | 47.94 ± 6.68 |
| Ashkenazi Jewish ancestry | 239 (0.66%) |
| Ethnicity (Black) | 828 (2.29%) |
| BRCA1 or BRCA2 germline pathogenic variants | 115 (462 tested) |
| Cancer diagnosis (all types) | 2 617 (7.24%) |
| Age at cancer onset (years) | 57.44 ± 15.96 |
| Colorectal cancer | 574 (1.59%) |
| Age at colorectal cancer onset (years) | 61.63 ± 17.19 |
| Lung/bronchus cancer | 153 (0.42%) |
| Age at lung/bronchus cancer onset (years) | 62.01 ± 26.18 |
| Pancreatic cancer | 136 (0.38%) |
| Age at pancreatic cancer onset (years) | 66.85 ± 22.94 |
| Ovarian cancer | 508 (1.40%) |
| Age at ovarian cancer onset (years) | 55.96 ± 22.84 |
N = 36,146 individuals.