Table 2.
Parameter | Mean [SD] |
Mean [SD] |
P-value |
---|---|---|---|
Spacer cohort (n=74) | Non-spacer cohort (n=136) | ||
Prostate-rectal separation achieved (mm) | 11.2 [3.3] | ||
Isotope, median number of seeds [range] | Pd, 57 [34 – 96] | Pd (n=109), 65 [15 – 109] | 0.001 |
I-125 (n=26), 77 [34 – 98] | |||
Isotope, median activity | Pd, 2.74 [1.54 – 4.02] | Pd, 2.29 [1.02 – 3.73] | 0.000 |
I-125, 0.46 [0.41 – 0.57] | |||
Prostate volume (cc) | 29.34 [12.35] | 34.55 [12.11] | 0.004 |
Prostate D90 (%) | 112.37 [12.04] | 109.60 [13.64] | 0.082 |
Prostate V100 (%) | 94.02 [3.81] | 93.08 [3.96] | 0.095 |
Prostate V150 (%) | 70.03 [8.44] | 65.64 [8.76] | 0.001 |
Prostate V200 (%) | 47.75 [9.02] | 41.50 [12.27] | 0.000 |
Urethra D20 (%) | 122.02 [17.27] | 118.87 [20.23] | 0.259 |
Urethra D5 (%) | 133.80 [22.75] | 130.91 [22.75] | 0.366 |
Urethra D1 (%) | 143.95 [25.38] | 143.07 [31.66] | 0.838 |
Rectal V100 (cc) | 0.01 [0.05] | 0.07 [0.19] | 0.000 |
Rectal D1cc (%) | 25.27 [12.67] | 52.74 [18.76] | 0.000 |
Rectal D2cc (%) | 20.47 [9.93] | 43.16 [15.70] | 0.000 |
D90 – dose to 90% of the prostate; prostate V100, V150 and V200 – prostate volumes receiving 100%, SD- standard deviation; 150% and 200% of the prescribed dose; urethra D20, D5 and D1 – percent of the prescribed dose to 20%, 5% and 1% of urethra; rectal V100 – rectal volume receiving 100% of prescribed dose; rectal D1cc and D2cc – percent of prescribed dose to 1cc and 2cc volumes of rectum.