Table 4. The results of ALMS1 gene polymorphism (rs 6748040) and early-onset MI risk.
| ALMS1 gene polymorphism (rs 6748040) | ||||||
|---|---|---|---|---|---|---|
| OR (95% CI) | z | P | OR adjust (95% CI) | z | P adjust | |
| Early-onset coronary artery disease | ||||||
| G vs. A | 1.036 (0.914–-1.175) | 0.56 | 0.577 | 1.028 (0.903–1.162) | 0.43 | 0.668 |
| GG vs. AA | 1.317 (0.950–1.826) | 1.65 | 0.098 | 1.306 (0.938–1.816) | 1.58 | 0.113 |
| Dominant genetic model | 1.352 (0.981–1.862) | 1.84 | 0.065 | 1.336 (0.973–1.846) | 1.77 | 0.076 |
| Recessive genetic model | 0.984 (0.843–1.148) | 0.21 | 0.835 | 0.991 (0.852–1.158) | 0.12 | 0.908 |
| Early-onset myocardial infarction | ||||||
| G vs. A | 1.371 (1.183–1.589) | 4.19 | 2.790 e-5 | 1.361 (1.172–1.577) | 4.07 | 4.688 e-5 |
| GG vs. AA | 2.037 (1.408–2.948) | 3.78 | 1.568 e-4 | 2.024 (1.394–2.935) | 3.71 | 2.054 e-4 |
| Dominant genetic model | 1.794 (1.254–2.567) | 3.20 | 1.000 e-3 | 1.780 (1.241–2.555) | 3.13 | 1.748 e-3 |
| Recessive genetic model | 1.421 (1.177–1.716) | 3.65 | 2.622 e-4 | 1.406 (1.160–1.702) | 3.48 | 4.939 e-4 |
Abbreviations: CI, confidence interval; OR, odds ratio.
Adjust confounding factors including age, gender, BMI, hypertension, diabetes, smoking, and biochemical indicators.