Fig. 9.

Reduced adherence of HGSC cells to collagen I by interference with CALB2 expression. OCMI cells from 3 different patients and OVCAR8 cells were treated with control (ctrl) or CALB2 siRNA pool (CR KD) for 96 h, detached from the culture dish and seeded on collagen type I‐coated wells. After 2 h, the adhered cells were stained with Crystal Violet and the optical density was measured at 595 nm. Significance was determined by unpaired, two‐tailed t‐test *: P < 0.05, **: P < 0.01, ***: P < 0.001, and ****: P < 0.0001. Data are shown for three triplicates each (mean ± standard deviation).