Table 2.
Characteristics of ovarian responses and laboratory data.
| Underweight (n = 42) | Normal (n = 800) | Overweight (n = 742) | Obese (n = 198) | P | |
|---|---|---|---|---|---|
| Fertilization rate (%) | |||||
| IVF | 29 (69%) | 608 (76%) | 552 (74.4%) | 152 (76.8%) | 0.649 |
| ICSI | 13 (31%) | 192 (24%) | 190 (25.6%) | 46 (23.2%) | 0.649 |
| Total Gn dosage (IU) | 1950 (1474, 2459) | 2175 (1650, 2625) | 2637 (2100, 3375)∗ | 3375 (2629, 4247)∗∗ | 0.001 |
| Gn stimulation, days | 12 (11, 13) | 12 (10, 13) | 12 (11, 15)∗ | 14 (12, 17)∗∗ | 0.001 |
| Oocytes retrieved (n) | 18.20 ± 6.15 | 19.16 ± 8.55 | 16.71 ± 8.27∗∗∗ | 14.95 ± 7.83∗∗ | 0.001 |
| E2 on HCG day (pg/mL) | 4936 (4830, 5060) | 4839 (3688, 4947)∗∗∗∗ | 4207 (2628, 4936)∗∗ | 3576 (2303, 4936)∗∗ | 0.001 |
| Progesterone on HCG day (ng/mL) | 1.39 ± 0.59 | 1.23 ± 0.55 | 1.11 ± 0.50∗ | 1.07 ± 0.52∗ | 0.001 |
| LH on HCG day (mIU/mL) | 1.03 (0.61, 1.46) | 0.99 (0.71, 1.32) | 0.93 (0.68, 1.22) | 0.92 (0.69, 1.19) | 0.074 |
| Endometrial thickness | 10.59 ± 1.87 | 10.88 ± 1.94 | 10.96 ± 1.93 | 11.19 ± 1.88 | 0.151 |
| Available embryos | 5.81 ± 3.44 | 5.75 ± 3.91 | 5.01 ± 3.56∗∗∗ | 4.84 ± 3.24∗∗∗ | 0.001 |
Continuous variables are presented as either mean ± standard deviation or median (interquartile range). Categorical variables are expressed as number and percentage. IVF: in vitro fertilization; ICSI: intracytoplasmic sperm injection; Gn: gonadotropin; E2: estradiol; LH: luteinizing hormone; HCG: human chorionic gonadotropin. ∗ significantly different vs. the underweight group and normal weight group. ∗∗ significantly different vs. the underweight group and normal weight group. ∗∗∗ significantly different vs. the normal weight group. ∗∗∗∗ significantly different vs. the normal weight group. ∗, ∗∗, ∗∗∗, and ∗∗∗∗ were significantly different.