Table 1.
The results of GSEA analysis in high- and low-risk groups determined by FCRLs.
| Pathway | Size | NES | NOM P value |
|---|---|---|---|
| High-risk group | |||
| KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS | 25 | 1.997 | <0.001 |
| KEGG_RNA_POLYMERASE | 29 | 1.849 | 0.008 |
| KEGG_AMINOACYL_TRNA_BIOSYNTHESIS | 41 | 1.848 | 0.008 |
| KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM | 16 | 1.726 | 0.014 |
| KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS | 11 | 1.611 | 0.03 |
| KEGG_LYSINE_DEGRADATION | 44 | 1.526 | 0.05 |
| Low-risk group | |||
| KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | 258 | -2.777 | <0.001 |
| KEGG_CHEMOKINE_SIGNALING_PATHWAY | 186 | -2.765 | <0.001 |
| KEGG_CELL_ADHESION_MOLECULES_CAMS | 131 | -2.716 | <0.001 |
| KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY | 130 | -2.694 | <0.001 |
| KEGG_VIRAL_MYOCARDITIS | 68 | -2.647 | <0.001 |
| KEGG_JAK_STAT_SIGNALING_PATHWAY | 151 | -2.634 | <0.001 |
| KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION | 79 | -2.578 | <0.001 |
| KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | 116 | -2.565 | <0.001 |
| KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 101 | -2.525 | <0.001 |
| KEGG_LEISHMANIA_INFECTION | 69 | -2.483 | <0.001 |
| KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 107 | -2.478 | <0.001 |
| KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS | 131 | -2.477 | <0.001 |
| KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 95 | -2.468 | <0.001 |
| KEGG_HEMATOPOIETIC_CELL_LINEAGE | 85 | -2.458 | <0.001 |
| KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY | 61 | -2.414 | <0.001 |
| KEGG_AUTOIMMUNE_THYROID_DISEASE | 50 | -2.39 | <0.001 |
| KEGG_APOPTOSIS | 86 | -2.34 | <0.001 |
| KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 74 | -2.318 | <0.001 |
| KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | 79 | -2.304 | <0.001 |