Table 1.
15 hub DEGs in the PPI networks.
| Gene symbol | Official full name | Degree | Expression in GC |
|---|---|---|---|
| FN1 | Fibronectin 1 | 64 | Upregulation |
| COL1A1 | Collagen type I alpha 1 chain | 45 | Upregulation |
| COL1A2 | Collagen type I alpha 2 chain | 42 | Upregulation |
| COL3A1 | Collagen type III alpha 1 chain | 41 | Upregulation |
| CD44 | CD44 molecule (Indian blood group) | 40 | Upregulation |
| SPARC | Secreted protein acidic and cysteine rich | 36 | Upregulation |
| FBN1 | Fibrillin 1 | 36 | Upregulation |
| BGN | Biglycan | 36 | Upregulation |
| UBE2C | Ubiquitin-conjugating enzyme E2 C | 35 | Upregulation |
| SPP1 | Secreted phosphoprotein 1 | 35 | Upregulation |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 35 | Upregulation |
| THBS1 | Thrombospondin 1 | 34 | Upregulation |
| COL5A2 | Collagen type I alpha 2 chain | 32 | Upregulation |
| CXCL8 | C-X-C motif chemokine ligand 8 | 31 | Upregulation |
| CCNB1 | Cyclin B1 | 31 | Upregulation |