Table 3.
Outcome variables | Baseline score or valuea (N=20) | 1-month follow-up score or valuea (N=20) | 3-month follow-up score or valuea (N=16) | |||
Quality of life |
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EORTC-QLQ-C30 b |
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Overall quality of life scalec | 76.70 (17.40) | 65.40 (16.10)d | 69.80 (12.10) | |
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Functioning scale e |
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Physical functioning | 93.70 (12.30) | 84.00 (17.30) | 90.80 (8.20) |
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Role functioning | 80.00 (29.80) | 72.50 (23.70) | 74.00 (20.60) |
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Emotional Functioning | 86.70 (13.20) | 76.70 (26.00) | 85.40 (20.70) |
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Cognitive functioning | 94.20 (11.80) | 90.00 (18.10) | 92.70 (11.40) |
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Social functioning | 71.70 (25.80) | 70.80 (22.90) | 65.60 (25.90) |
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General symptom scale f |
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Fatigue | 10.00 (12.30) | 36.10 (19.70)g | 20.80 (23.10) |
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Nausea and vomiting scale | 5.00 (11.60) | 12.50 (22.90) | 5.20 (15.90) |
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Pain | 3.30 (6.50) | 15.80 (18.20)g | 12.50 (15.70)d |
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Dyspnea | 3.30 (14.20) | 25.00 (17.40)g | 20.80 (27.70) |
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Insomnia | 23.30 (32.70) | 30.00 (32.40) | 22.90 (35.60) |
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Appetite loss | 6.70 (22.10) | 20.00 (26.00) | 20.80 (27.70) |
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Constipation | 11.70 (21.30) | 13.30 (21.60) | 16.70 (28.00) |
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Diarrhea | 6.70 (13.00) | 13.30 (19.00) | 12.50 (15.70) |
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Financial difficulties | 36.70 (28.90) | 28.30 (33.00) | 29.20 (25.20) |
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EORTC-QLQ-OES18 h |
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General functional scale e |
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Dysphagia | 68.30 (33.80) | 62.80 (27.50) | 68.10 (29.60) |
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General symptom scale f |
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Trouble swallowing saliva | 36.70 (44.70) | 31.70 (39.10) | 26.70 (37.60) |
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Choked when swallowing | 16.70 (28.20) | 23.30 (25.40) | 28.90 (33.10) |
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Eating | 6.70 (14.70) | 25.80 (18.20)g | 21.70 (16.40)d |
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Dry mouth | 20.00 (28.00) | 23.30 (25.40) | 6.70 (12.90)d |
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Trouble with taste | 5.00 (21.30) | 11.70 (23.60) | 2.20 (8.10) |
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Trouble with coughing | 11.70 (18.60) | 38.30 (33.00)d | 15.60 (20.00) |
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Trouble talking | 0.00 (0.00) | 43.30 (29.30)g | 17.80 (20.00)g |
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Reflux | 5.00 (14.60) | 23.30 (26.90)d | 25.60 (31.70) |
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Pain | 8.30 (14.10) | 10.60 (12.10) | 10.40 (13.30) |
Nutrition status |
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Weight (kg) | 60.00 (8.70) | 56.30 (7.80)g | 55.00 (8.00)g | ||
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BMI (kg/m2) | 21.50 (3.30) | 20.50 (2.60)d | 20.00 (2.60)d | ||
Physical fitness |
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6MWDi (m) | 506 (330.00-558.00) | 469 (276.00-612.00) | 486 (343.00-682.00) | ||
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6MWD changej | N/Ak | 0.95 (0.67-1.43) | 1.03 (0.83-1.24) | ||
Psychological measures |
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PHQ-9l | 1.11 (1.33) | 5.00 (4.61)d | 2.81 (3.56) | ||
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GAD-7m | 3.50 (4.16) | 4.20 (4.54) | 2.65 (3.52) | ||
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PSS-10n | 10.30 (4.54) | 12.60 (6.61) | 10.65 (7.03) | ||
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Depressed, n (%) | 0 (0) | 3 (15) | 1 (6) | ||
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Anxiety, n (%) | 4 (20) | 4 (20) | 2 (12) |
aData are presented as mean (SD), n (%), or median (range).
bEORTC-QLQ-C30: European Organization for Research and Treatment of Cancer-Quality of life Question-Core-30.
cHigher scores indicate better health.
dP<.05.
eHigher scores indicate better function.
fHigher scores indicate worse symptoms.
gP<.01.
hEORTC-QLQ-OES-18: European Organization for Research and Treatment of Cancer-Quality of life Question-Oesophageal Cancer Module-18.
i6MWD: 6-minute walk distance.
j6MWD change was calculated using follow-up 6MWD values divided by baseline 6MWD values.
kN/A: not applicable.
lPHQ-9: Patient Health Questionnaire-9.
mGAD-7: General Anxiety Disorder-7.
nPSS-10: Perceived Stress Scale-10.