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. 2020 Aug 18;22(8):e18946. doi: 10.2196/18946

Table 3.

Results of the outcome variables.

Outcome variables Baseline score or valuea (N=20) 1-month follow-up score or valuea (N=20) 3-month follow-up score or valuea (N=16)
Quality of life



EORTC-QLQ-C30 b




Overall quality of life scalec 76.70 (17.40) 65.40 (16.10)d 69.80 (12.10)


Functioning scale e





Physical functioning 93.70 (12.30) 84.00 (17.30) 90.80 (8.20)



Role functioning 80.00 (29.80) 72.50 (23.70) 74.00 (20.60)



Emotional Functioning 86.70 (13.20) 76.70 (26.00) 85.40 (20.70)



Cognitive functioning 94.20 (11.80) 90.00 (18.10) 92.70 (11.40)



Social functioning 71.70 (25.80) 70.80 (22.90) 65.60 (25.90)


General symptom scale f




Fatigue 10.00 (12.30) 36.10 (19.70)g 20.80 (23.10)



Nausea and vomiting scale 5.00 (11.60) 12.50 (22.90) 5.20 (15.90)



Pain 3.30 (6.50) 15.80 (18.20)g 12.50 (15.70)d



Dyspnea 3.30 (14.20) 25.00 (17.40)g 20.80 (27.70)



Insomnia 23.30 (32.70) 30.00 (32.40) 22.90 (35.60)



Appetite loss 6.70 (22.10) 20.00 (26.00) 20.80 (27.70)



Constipation 11.70 (21.30) 13.30 (21.60) 16.70 (28.00)



Diarrhea 6.70 (13.00) 13.30 (19.00) 12.50 (15.70)



Financial difficulties 36.70 (28.90) 28.30 (33.00) 29.20 (25.20)

EORTC-QLQ-OES18 h



General functional scale e




Dysphagia 68.30 (33.80) 62.80 (27.50) 68.10 (29.60)


General symptom scale f




Trouble swallowing saliva 36.70 (44.70) 31.70 (39.10) 26.70 (37.60)



Choked when swallowing 16.70 (28.20) 23.30 (25.40) 28.90 (33.10)



Eating 6.70 (14.70) 25.80 (18.20)g 21.70 (16.40)d



Dry mouth 20.00 (28.00) 23.30 (25.40) 6.70 (12.90)d



Trouble with taste 5.00 (21.30) 11.70 (23.60) 2.20 (8.10)



Trouble with coughing 11.70 (18.60) 38.30 (33.00)d 15.60 (20.00)



Trouble talking 0.00 (0.00) 43.30 (29.30)g 17.80 (20.00)g



Reflux 5.00 (14.60) 23.30 (26.90)d 25.60 (31.70)



Pain 8.30 (14.10) 10.60 (12.10) 10.40 (13.30)
Nutrition status



Weight (kg) 60.00 (8.70) 56.30 (7.80)g 55.00 (8.00)g

BMI (kg/m2) 21.50 (3.30) 20.50 (2.60)d 20.00 (2.60)d
Physical fitness



6MWDi (m) 506 (330.00-558.00) 469 (276.00-612.00) 486 (343.00-682.00)

6MWD changej N/Ak 0.95 (0.67-1.43) 1.03 (0.83-1.24)
Psychological measures



PHQ-9l 1.11 (1.33) 5.00 (4.61)d 2.81 (3.56)

GAD-7m 3.50 (4.16) 4.20 (4.54) 2.65 (3.52)

PSS-10n 10.30 (4.54) 12.60 (6.61) 10.65 (7.03)

Depressed, n (%) 0 (0) 3 (15) 1 (6)

Anxiety, n (%) 4 (20) 4 (20) 2 (12)

aData are presented as mean (SD), n (%), or median (range).

bEORTC-QLQ-C30: European Organization for Research and Treatment of Cancer-Quality of life Question-Core-30.

cHigher scores indicate better health.

dP<.05.

eHigher scores indicate better function.

fHigher scores indicate worse symptoms.

gP<.01.

hEORTC-QLQ-OES-18: European Organization for Research and Treatment of Cancer-Quality of life Question-Oesophageal Cancer Module-18.

i6MWD: 6-minute walk distance.

j6MWD change was calculated using follow-up 6MWD values divided by baseline 6MWD values.

kN/A: not applicable.

lPHQ-9: Patient Health Questionnaire-9.

mGAD-7: General Anxiety Disorder-7.

nPSS-10: Perceived Stress Scale-10.