. 2020 Aug 12;25(16):3671. doi: 10.3390/molecules25163671

Table 4.

In vivo anti-inflammatory effect of LSEO using carrageenan induced-paw edema.

Treatment (Dose μg/kg)	Weight (mean, mg) ± SD			% Inhibition of Edema
Treatment (Dose μg/kg)	Left Hind Paw	Right Hind Paw	Edema Weight ^#	% Inhibition of Edema
LSEO (200)	126.10 ± 8.00	110.12 ± 7.12	15.975 ± 7.31 ^A	47.0588
LSEO (20)	138.48 ± 10.1	121.00 ± 6.72	17.480 ± 8.71 ^A	42.0712
LSEO (2)	146.08 ± 8.61	122.35 ± 6.00	23.733 ± 9.22 ^A,B	21.3476
Positive control (Indomethacin)	161.25 ± 6.12	144.50 ± 6.18	16.750 ± 7.50 ^A	44.4904
Negative control	154.30 ± 7.65	124.12 ± 10.0	30.175 ± 13.41 ^B	/

Groups of animals (n = 5 mice per group) were pretreated with vehicle, Indomethacin (25 mg/kg, p.o.) or LSEO at doses of 2, 20, and 200 mg/kg per os (p.o.) 30 min before carrageenan-induced paw edema. LSEO: Lavandula stoechas Essential Oil. ^# Means within the same column followed by the same capital letter are not significantly different (p > 0.05) according to ANOVA analysis followed by Tukey’s post hoc multiple comparison test.