Table 4.
Comparison of PTC with FTC according to clinical course.
| Characteristics | PTC (n = 62), n (%) | FTC (n = 17), n (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Inoperable | Initial-DM Group | Late-DM Group | L-R Group | p-Value (A vs. B vs. C) | Inoperable | Initial-DM Group | Late-DM Group ‡ | L-R Group ‡ | p-Value (A vs. B vs. C) | ||
| Number of patients | 4 (6.5) | 21 (33.9) | 23 (37.1) | 14 (22.6) | 2 (11.8) | 12 (70.6) | 1 (5.9) | 2 (11.8) | |||
| Sex | Female | 4 (100.0) | 9 (42.9) | 13 (56.5) | 11 (78.6) | 0.112 | 2 (100.0) | 12 (100.0) | 0 | 1 | 0.02 |
| Age | <55 | 1 (25.00) | 6 (28.6) | 3 (13.0) | 2 (14.3) | 0.439 | 0 (0.0) | 3 (25.0) | 0 | 1 | >0.99 |
| 55 or more | 3 (75.0) | 15 (71.4) | 20 (87.0) | 12 (85.7) | 2 (100.0) | 9 (75.0) | 1 | 1 | |||
| Primary tumor size † | <4 cm | 1 (25.00) | 13 (61.9) | 20 (87.0) | 10 (71.4) | 0.160 | 2 (100.0) | 11 (91.7) | 1 | 1 | 0.554 |
| 4 cm or more | 3 (75.0) | 8 (38.1) | 3 (13.0) | 4 (28.6) | 0 (0.0) | 1 (8.3) | 0 | 1 | |||
| pT | 1 | - | 2 (9.5) | 3 (13.0) | 1 (7.1) | 0.371 | - | 3 (25.0) | 0 | 0 | >0.99 |
| 2 | - | 1 (4.8) | 0 (0.0) | 3 (21.4) | - | 3 (25.0) | 1 | 1 | |||
| 3 | - | 11 (52.4) | 9 (39.1) | 5 (35.7) | - | 4 (33.3) | 0 | 1 | |||
| 4 | - | 7 (33.3) | 11 (47.8) | 5 (35.7) | - | 2 (16.7) | 0 | 0 | |||
| pN | Not assessed | - | 0 (0.0) | 1 (4.3) | 1 (7.1) | 0.430 | - | 1 (8.3) | 0 | 0 | >0.99 |
| N0 | - | 4 (19.0) | 8 (34.8) | 6 (42.9) | - | 11 (91.7) | 1 | 2 | |||
| N1a | - | 4 (19.0) | 5 (21.7) | 3 (21.4) | - | 0 | 0 | 0 | |||
| N1b | - | 13 (61.9) | 9 (39.1) | 4 (28.6) | - | 0 | 0 | 0 | |||
| Lymphovascular invasion | Yes | - | 6 (28.6) | 2 (8.7) | 1 (7.1) | 0.177 | - | 8 (66.7) | 1 | 1 | >0.99 |
| Resection margin | Positive | - | 8 (38.1) | 9 (39.1) | 2 (14.3) | 0.239 | - | 1 (8.3) | 0 | 0 | >0.99 |
| Extent to central LN | Yes | - | 14 (66.7) | 11 (47.8) | 6 (42.9) | 0.301 | - | 0 | 0 | 0 | - |
| Extent to lateral LN | Yes | - | 13 (61.9) | 9 (39.1) | 4 (28.6) | 0.118 | - | 0 | 0 | 0 | - |
| Extent of surgery | Total | - | 21 (100.0) | 22 (95.7) | 13 (92.9) | 0.708 | - | 10 (83.3) | 1 | 1 | 0.516 |
| Less than total | - | 0 (0.0) | 1 (4.3) | 1 (7.1) | - | 2 (16.7) | 0 | 1 | |||
A, initial-DM group; B, late-DM group; C, L-R group, Categorical variables are shown as number (percentage) and continuous variables are shown as median (interquartile range). n, number of patients; Not assessed, lymph nodes were not assessed during surgery; LN, lymph node; Total, total thyroidectomy. A, initial-DM group; B, late-DM group; C, L-R group; PTC, papillary thyroid carcinoma; FTC, follicular thyroid carcinoma. † Primary tumor size in inoperable group was measured by thyroid ultrasound. ‡ Because of the small number of enrolled patients, we did not calculate percentages in the late-DM and L-R groups in FTC patients.