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PIC formation on HomolD-box-containing promoters. In the first step of PIC formation, the transcription factor Rrn7 binds to the HomolD-box (I), which in turn is able to recruit the TBP-TFIIB complex (II). After TBP-TFIIB are recruited to the complex, it follows the binding of RNAPII-TFIIF (III), and then the TFIIE and TFIIH are recruited to the complex to form the complete PIC (IV).
