. 2020 Aug 6;9(8):2538. doi: 10.3390/jcm9082538

Table 1.

Characteristics of study participants.

Subjects	Tot	M/F	Age at MRI (y; Mean ± SD)	Age at Onset (y; Mean ± SD)	Disease Duration at the Time of MRI (m; Mean ± SD)	ALSFRS-R (Mean ± SD)	Phenotype at Onset
Subjects	Tot	M/F	Age at MRI (y; Mean ± SD)	Age at Onset (y; Mean ± SD)	Disease Duration at the Time of MRI (m; Mean ± SD)	ALSFRS-R (Mean ± SD)	Prevalent UMN	Bulbar	Classic	Prevalent LMN
Patients *	93	55/38	62.8 ± 10.1	60.8 ± 10.7	25 ± 31	40.4 ± 6.2	14 (15%)	14 (15%)	47 (50.5%)	18 (19.5%)
Controls	89	56/33	60.2 ± 9.5	/	/	/	/	/	/	/
		p = 0.6 (χ2-test)	p = 0.08 (t-test)	/	/	/	/	/	/	/

* 12 patients had a mutation (6 had an SOD1 mutation, 5 had a C9ORF72 mutation, and 1 had a TDP43 mutation). M, male; F, female; y, years; m, months; SD = standard deviation; ALSFR-R, revised ALS Functional Rating Scale; UMN, upper motor neuron; LMN, lower motor neuron; MRI, Magnetic Resonance Imaging.