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. 2020 Aug 12;9(8):2615. doi: 10.3390/jcm9082615

Figure 1.

Figure 1

mRNA expression levels of IRS1, p85α, p110β and p85α/p110β ratio in VAT from non-obese patients and in patients with morbid obesity with low insulin resistance (MO-low-IR), with high insulin resistance (MO-high-IR), and with T2DM under treatment with metformin (MO-metf-T2DM). Gene expression was assessed using the 2-∆∆Ct method. Results are represented as mean ± SEM. * p < 0.05 with regard to non-obese patients.