Figure 4.

The expression of inflammatory markers and extracellular matrix in different cybrids after hypoxia-ischemia. Comparisons of inflammatory cytokines in cybrid cells harboring stroke-susceptible haplogroup F and resistant haplogroup B. Western blot analysis shows hypoxia induced protein expression of IL-1β (A), IL-6 (B), TNF-α (C), and MMP-9 (D). Actin was used as loading controls. Data represent the mean ± SD of at least three independent experiments (* p < 0.05; ^# p < 0.005). N was used to represent normoxic and H to represent the hypoxic condition.