Table 1.
Clinical characteristics of patients (pts) included in the study. Ref: refractory to BTZ and lenalidomide treatments.
| pts | Sex | Age | Status Disease | Ig Type | R-ISS Stage | LDH (U/L) | Hb (g/dL) | ANC/mmc | ALC/mmc | AMC/mmc | k-lambda sFLC Ratio | FISH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| p#1 | M | 49 | Ref | IgAlambda | 1 | 213 | 11.6 | 900 | 540 | 800 | 0.01 | t (4;14) |
| p#2 | M | 72 | Ref | IgGk | 3 | 315 | 9.8 | 1670 | 560 | 870 | 230 | t (11;14) |
| p#3 | M | 58 | Ref | IgGk | 3 | 280 | 9.7 | 1890 | 700 | 910 | 120 | t (4;14) |
| p#4 | M | 73 | Ref | IgGk | 3 | 654 | 6.5 | 310 | 560 | 650 | 210 | del17p13 |
| p#5 | F | 68 | Ref | IgGlambda | 3 | 310 | 8.9 | 1100 | 780 | 760 | 0.01 | del17p13 |
LDH: lactate dehydrogenase; Hb: hemoglobin; ANL: absolute neutrophil count; ALC: absolute lymphocyte count; AMC: absolute monocytic count; sFLC: serum Free Light Chains.