Table 1.
Effect of ASBE, nano-extracts, and their combination with nano-Ag on the macroscopic parameters of ulcerative colitis.
| Group | Weight/Length Ratio (g/cm) | Lesion Score (0–5) | Ulcer Area (mm2) | Ulcer Index (UI) | Mortality (Dead/Total%) |
|---|---|---|---|---|---|
| Control Negative | 0.127 ± 0.007 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0/6 (0.0%) |
| Control Positive | 0.251 ± 0.028 a | 5.50 ± 0.879 a | 18.75 ± 0.994 a | 24.25 ± 1.546 a | 1/6 (16.66%) |
| Dexamethasone | 0.155 ± 0.016 * | 3.97 ± 0.590 *a | 11.75 ± 1.258 *a | 15.72 ± 1.118 *a | 1/6 (16.66%) |
| Nano Ag | 0.151 ± 0.004 * | 4.00 ± 0.182 *a | 8.87 ± 1.250 *a | 12.87 ± 1.109 *a | 0/6 (0.0%) |
| ASBE | 0.202 ± 0.013 *a | 4.20 ± 0.258 *a | 13.50 ± 0.577 *a | 17.70 ± 0.365 *a | 1/6 (16.66%) |
| ASBE + Nano Ag | 0.174 ± 0.011 *a | 4.02 ± 0.427 *a | 8.62 ± 1.109 *a | 12.65 ± 1.318 *a | 0/6 (0.0%) |
| ASB Nano ext. | 0.193 ± 0.015 *a | 4.17 ± 0.550 *a | 9.95 ± 0.823 *a | 14.14 ± 0.842 *a | 1/6 (16.66%) |
| ASB Nano ext. + Nano Ag | 0.146 ± 0.010 * | 3.50 ± 0.294 *a | 8.50 ± 1.291 *a | 12.00 ± 1.010 *a | 0/6 (0.0%) |
Results are presented as mean ± SD (n = 6). p < 0.05 compared to the positive control, one-way ANOVA followed by Tukey test. a Statistically significant from control negative. * Statistically significant from control positive at p < 0.05.