Table 1.

Interest copper resistance markers from Acidithiobacillus. MFP, membrane fusion protein.

Protein	Functional Description *
CopA	Copper-exporting P-type ATPase A, exports Cu+ from the cytoplasm to the periplasm; binds 2 Cu+ ions per monomer, which are transferred to periplasmic copper chaperone CusF upon ATP hydrolysis.
CopB	Copper-exporting P-type ATPase B, copper-translocating outer membrane protein.
CopZ	Copper chaperone, ion-binding protein delivering two Cu+ ions to the copper-transporting ATPase CopA.
CusA	Cation efflux system protein, copper efflux RND transporter permease.
CusB	Cation efflux system protein, copper efflux pump MFP component.
CusC	Cation efflux system protein RND transporter outer membrane channel component
CusF	Cation efflux system protein, periplasmic copper-binding chaperone component.
RusA	Rusticyanin type A, high potential iron sulfur protein, blue copper cupredoxin.
RusB	Rusticyanin type B, high potential iron sulfur protein, blue copper cupredoxin.
Acop	Acidophile cytochrome c oxidase partner, green copper cupredoxin [5].

* information collected from UniProt (https://www.uniprot.org/).