Skip to main content
. 2020 Aug 11;9(8):1879. doi: 10.3390/cells9081879
CSCs Cancer stem cells
MALM Mastermind-like proteins
Hes Hairy enhancer of split genes
Dll Delta-like ligand
Jag Jagged
T-ALL T-cell acute lymphoblastic leukemia
CLL Chronic lymphocytic leukemia
N1ICD Notch1 intracellular domain
Lnfg Lunatic fringe
Mnfg Maniac fringe
ALDH1 Aldehyde dehydrogenase 1
VEGF Vascular endothelial growth factor
MAPK Mitogen activated protein kinase
EMT Epithelial to mesenchymal transition
TLR Toll-like receptor
TAMs Tumor-associated macrophages
Ngn2 Neurogenin2
AGM Aorta-Gonad Mesonephros
HSC Hematopoietic stem cells
ISC Intestinal stem cells
ABCG2 ATP-binding cassette super family G member 2
CD Cluster of differentiation
LSC Leukemia stem cells
AML Acute myeloid leukemia
LIC Leukemia initiating cells
BMSCs Bone marrow mesenchymal stromal/stem cells
CMML Chronic myelomonocytic leukemia
BCSCs Breast cancer stem cells
ER Estrogen receptor
DCIS Ductal carcinoma in situ
Epo Erythropoietin
APC Adenomatous polyposis coli
HNSCC Head and neck squamous cell carcinoma
OSCC Oral squamous cell carcinoma
ESA Epithelial-specific antigen
NSCLC Non-small cell lung cancer
LSCC Lung squamous cell carcinoma
MM Malignant melanoma
NMSC Non-melanoma skin cancer
BCC Basal cell carcinoma
DMBA 7,12-dimethylbenz[a]anthracene
GSIs Gamma secretase inhibitors
APP β-amyloid precursor protein
β-amyloid
mAbs Monoclonal antibodies
IMR-1 Inhibitor of Mastermind Recruitment-1
dnMAML Truncated MAML
NRR Negative regulatory region
NECD Notch extracellular domain
NICD Notch intracellular domain
EGF Epidermal growth factor
ANK Ankyrin
PEST Proline, glutamic acid, serine, and threonine-rich domain
MNNL Module at the N-terminus of Notch ligands
SP Signaling peptide