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Increased expression of p21 in cells exhibiting G2/M phase arrest. HT-29 cells were treated for 24 h with 30 nM of OAT-449, vincristine or DMSO as a control. Cells were stained with anti-p21-FITC antibody and propidium iodide, with 10,000 cells analyzed per sample. Plots shown are representative of at least three independent experiments.
