Figure 10.

Individual scoring parameters of the Sellers score for (a) cellular morphology, (b) tissue filling, (c) % new subchondral bone, (d) architecture within the defect, (e) surface architecture, (f) new tidemark formation (g) new cartilage matrix staining, and (h) cartilage integration with surrounding cartilage between groups in a focal early OA model. * p < 0.05 from Kruskal-Wallis test with Dunn’s multiple comparison test. (i) The overall Sellers score for cartilage repair in a focal early OA model. * p < 0.05 from one way ANOVA with Tukey post-hoc test, ^# p < 0.05 from pairwise t-test. The data represent the mean ± S.D. of n = 6–8 rabbits with dots representing the mean from three blinded scorers (five sections per defect).