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. 2020 Aug 8;25(16):3610. doi: 10.3390/molecules25163610

Table 1.

EC50 (µM) values of compound 1, and hybrid 8-hydroxyquinoline-indole derivatives 7a–7e, 12a–12b and 18a–18h against self-induced Aβ1–42 aggregation in thioflavin T (ThT)-fluorescence assays.

Compd. 1 7a 7b 7c 7d 7e 12a 12b
1–42 9.95 4.26 9.28 3.22 6.34 9.52 >10 >10
Compd. 18a 18b 18c 18d 18e 18f 18g 18h
1–42 >10 >10 1.72 1.48 2.49 1.08 >10 2.58