Table 2.
Comparison of lymphoma and B cell associated manifestations between male and female patients with Sjögren’s syndrome (female control population was matched in a 1:2 ratio based on SS age onset and disease duration).
| FEATURE | Females (n = 192) | Males (n = 96) | p-Value |
|---|---|---|---|
| Palpable purpura | 9% (17/192) | 10% (10/96) | 0.8302 |
| Vasculitic ulcer | 2% (3/192) | 1% (1/96) | 1 |
| Glomerulonephritis | 0.5% (1/191) | 3% (3/96) | 0.1106 |
| Peripheral nerve involvement | 2% (4/192) | 3% (3/96) | 0.6895 |
| Lymphadenopathy | 9% (18/192) | 17% (16/95) | 0.0994 |
| Central nervous system involvement | 2% (3/192) | 2% (2/96) | 1 |
| Lymphoma | 5% (10/191) | 18% (17/96) | 0.0013 |
| MALT | 80% (8/10) | 76% (13/17) | 0.99 |
| DLBCL | 10% (1/10) | 18% (3/17) | 0.99 |
Bold text indicates a statistically significant difference with a p-value less than 0.05.