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Antibiotic effect of tobramycin (Tob) in presence and absence of itaconic acid (IA) on PA14 wt biofilm grown in PPGAS medium for 24 h: biofilms were treated for 6 h with 50 µg/mL Tob either alone or in combination with IA (molar [Tob]:[IA] of 1:5). Cfu/mL values are depicted logarithmically for n = 3 experiments with technical triplicates each. Untreated PA14 wt biofilms served as controls. * is for p < 0.05 vs. controls. • represents mean value.
