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. 2020 Jul 27;9(8):1789. doi: 10.3390/cells9081789

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The molecular function of deregulated proteins in Prm2-deficient sperm. (A) Volcano plots displaying DE proteins in pairwise comparison of Prm2^+/+ (WT), Prm2^+/− (HET) and Prm2^−/− (KO) samples. (B) Reactome pathway analysis of proteins downregulated in Prm2^-/- sperm compared to wildtype (|log₂ FC| > 1; FDR < 0.1). FDR is given in each bar. (C) STRING analysis of proteins downregulated in Prm2^−/− sperm compared to wildtype (|log₂ FC| > 1; FDR < 0.1). Proteins involved in biological processes of hydrogen peroxide metabolism are highlighted in blue.

The molecular function of deregulated proteins in Prm2-deficient sperm. (A) Volcano plots displaying DE proteins in pairwise comparison of Prm2^+/+ (WT), Prm2^+/− (HET) and Prm2^−/− (KO) samples. (B) Reactome pathway analysis of proteins downregulated in Prm2^-/- sperm compared to wildtype (|log₂ FC| > 1; FDR < 0.1). FDR is given in each bar. (C) STRING analysis of proteins downregulated in Prm2^−/− sperm compared to wildtype (|log₂ FC| > 1; FDR < 0.1). Proteins involved in biological processes of hydrogen peroxide metabolism are highlighted in blue.