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. 2020 Jul 24;11(8):717. doi: 10.3390/mi11080717

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Release profiles of (a) IBU-loaded CaCO₃ crystals and (b) IBU-loaded (PRO/PSS)₅-coated CaCO₃ crystals in simulated gastric fluid for the first 30 min, followed by simulated intestinal fluid for the remaining time, at 37 °C. Figure taken with permission from Reference [106], copyright© 2006, Elsevier.