Table 2.
The 10 discovered variants of the mobilized colistin resistance (mcr) gene, with their species and country of first detection, as well as their sequence homology to mcr-1.
| mcr Gene Type | Species of First Detection | Country of First Detection | Sequence Homology to mcr-1 (%) | Strain Information | Reference |
|---|---|---|---|---|---|
| mcr-1 | Escherichia coli | China | 100 | SHP45 | [123] |
| mcr-2 | E. coli | Belgium | 76.7 | CP011374 | [128] |
| mcr-3 | E. coli | China | 45 | WJ1 | [129] |
| mcr-4 | Salmonella enterica serovar Typhimurium | Italy | 34 | R3445 | [130] |
| mcr-5 | S. enterica subsp. enterica | Germany | 63.89 | 11-00422 | [131] |
| mcr-6 | Moraxella pluranimalium | Great Britain | 62 | 248-01T/DSM-22804) | [132] |
| mcr-7 | Klebsiella pneumoniae | China | 65 | SC20141012 | [133] |
| mcr-8 | K. pneumoniae | China | 31.08 | KP91 | [134] |
| mcr-9 | S. enterica subsp. enterica | New York | 63 | GCF_002091095.1 | [135] |
| mcr-10 | Enterobacter roggenkampii | China | 29.31 | 090065 (WCHER090065) | [125] |