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Dorsal ruffles on activated macrophages. Scanning electron micrograph of dorsal plasma membrane ruffles (pseudocoloured yellow) in CSF-1-activated bone marrow-derived macrophages. Deficiency of SNX5 results in a dramatic reduction in dorsal ruffling and macropinocytosis. Micrograph taken by Dr Prajakta Gosavi from article by Lim et al. [9] (3500× magnification).
