Table 2.
Efficacy analysis of the effects of exergame intervention in patients with fibromyalgia on the different brain structures, the pVO2, and the MMSE.
| Variables | Between Group Comparison | Within Group Comparison | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Brain Areas (cm³) | Groups | Pre Median (IQR) | Post Median (IQR) | Value of the Contrast | p-Value | Effect Size | Value of the Contrast | p-Value | Effect Size |
| L. Hippocampus | EG | 3.04 (0.43) | 3.15 (0.22) | −0.342 | 0.925 | −0.020 | −2.738 | 0.016 | −0.323 |
| CG | 2.93 (0.36) | 3.07 (0.24) | −2.372 | 0.039 | −0.438 | ||||
| R. Hippocampus | EG | 3.08 (0.31) | 3.26 (0.36) | −0.075 | 0.925 | 0.071 | −3.011 | 0.013 | −0.354 |
| CG | 3.07 (0.33) | 3.15 (0.26) | −2.220 | 0.048 | −0.354 | ||||
| L. Insula | EG | 3.35 (2.06) | 5.08 (3.16) | 0.013 | 0.925 | 0.053 | −3.320 | 0.007 | −1.037 |
| CG | 3.34 (2.49) | 5.93 (1.12) | −2.896 | 0.016 | −1.245 | ||||
| R. Insula | EG | 3.82 (1.70) | 5.76 (2.41) | −0.450 | 0.925 | 0.000 | −2.516 | 0.022 | −0.578 |
| CG | 4.28 (1.21) | 5.87 (1.23) | −2.451 | 0.036 | −0.751 | ||||
| L. Amygdala | EG | 1.37 (0.19) | 1.39 (0.17) | −0.501 | 0.925 | -0.090 | −0.633 | 0.527 | 0.088 |
| CG | 1.41 (0.16) | 1.39 (0.11) | −0.087 | 0.931 | 0.003 | ||||
| R. Amygdala | EG | 1.63 (0.18) | 1.68 (0.27) | −0.103 | 0.925 | 0.197 | −2.776 | 0.016 | −0.329 |
| CG | 1.64 (0.22) | 1.65 (0.15) | −1.860 | 0.091 | −0.290 | ||||
| L. Thalamus | EG | 7.83 (0.94) | 7.72 (0.80) | −0.918 | 0.925 | −0.145 | −4.107 | 0.020 | 0.272 |
| CG | 7.51 (0.61) | 7.41 (0.65) | −4.074 | 0.075 | 0.208 | ||||
| R. Thalamus | EG | 7.07 (0.81) | 6.95 (0.73) | −1.599 | 0.371 | −0.338 | −1.834 | 0.097 | 0.153 |
| CG | 6.81 (0.66) | 6.74 (0.48) | −0.991 | 0.373 | −0.037 | ||||
| L. Cerebellum | EG | 48.37 (9.92) | 50.80 (8.43) | 1.601 | 0.706 | -0.397 | −1.705 | 0.114 | −0.158 |
| CG | 46.12 (8.09) | 48.27 (5.87) | −2.833 | 0.016 | −0.466 | ||||
| R. Cerebellum | EG | 51.39 (13.14) | 52.00 (6.91) | −1.483 | 0.377 | -0.489 | −1.282 | 0.236 | −0.093 |
| CG | 49.04 (11.27) | 50.36 (8.96) | −2.798 | 0.016 | −0.426 | ||||
| Total Cerebral GM | EG | 436.10 (72.50) | 507.24 (92.04) | −0.595 | 0.814 | -0.177 | −3.750 | < 0.001 | −0.939 |
| CG | 428.35 (126.54) | 521.54 (71.29) | −2.972 | 0.016 | −0.965 | ||||
| pVO2 (ml/Kg/min) | EG | 23.77 (4.24) | 24.51 (3.86) | −1.911 | 0.371 | 0.462 | −0.807 | 0.455 | −0.108 |
| CG | 23.62 (5.23) | 23.02 (5.52) | −1.601 | 0.142 | 0.132 | ||||
| MMSE | EG | 29.00 (1.00) | 29.00 (2.50) | −0.983 | 0.706 | −0.108 | −1.996 | 0.075 | 0.404 |
| CG | 28.00 (2.00) | 28.00 (4.00) | −0.945 | 0.373 | 0.248 | ||||
Abbreviations: IQR, interquartile range; GM, gray matter; pVO2, peak volume oxygen consumption; MMSE, mini-mental state examination; EG, exercise group; CG, control group; L, left; R, right.