Table 4.
Compound | MIC (μg/mL) | IC50 (μM) | ||
---|---|---|---|---|
S. aureus | M. smegmatis | A549 | Hela | |
1 | 14.6 ± 0.3 | 12.4 ± 0.3 | 25.7 ± 0.4 | 34.7 ± 0.6 |
2 | 28.1 ± 0.4 | 35.1 ± 0.6 | 46.6 ± 0.4 | 50.2 ± 0.5 |
3 | 9.2 ± 0.2 | 5.2 ± 0.2 | 0.6 ± 0.2 | 0.4 ± 0.2 |
5 | 8.1 ± 0.2 | 7.7 ± 0.2 | 0.9 ± 0.2 | 1.1 ± 0.3 |
erythromycin | 7.6 ± 0.2 | 4.5 ± 0.2 | NA | NA |
doxorubicin | NA | NA | 0.1 ± 0.0 | 0.5 ± 0.1 |