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. 2020 Jul 22;12(8):2012. doi: 10.3390/cancers12082012
Abbreviation Meaning
ABCG2 ATP-binding cassette transporter G2
ACACB Acetyl-CoA carboxylase beta
Akt Protein kinase B
ALDH1A1 Aldehyde dehydrogenase 1 family member A1
AR Androgen receptor
AREG Amphiregulin
ATM Ataxia telangiectasia mutated
ATP Adenosine triphosphate
AUC Area under the curve
AURKA Aurora kinase A
B-MYB Myb-related protein B
BC Breast cancer
BCL2 B-cell lymphoma 2
BCL9 B-cell CLL/lymphoma 9
BIRC2 Baculoviral IAP repeat containing 2
BIRC3 Baculoviral IAP repeat containing 3
BL1 Basal-like 1
BL2 Basal-like 2
BLIA Basal-like immune activated subtype
BLIS Basal-like immunosuppressed subtype
BRCA1 Breast cancer gene 1
BRCA2 Breast cancer gene 2
CCL5 Chr. chemokine ligand 5
CCND1 Cyclin D1
CCND2 Cyclin D2
CCND3 Cyclin D3
CD20 Cluster of differentiation 20
CD3 Cluster of differentiation 3
CD37 Cluster of differentiation 37
CD3D Cluster of differentiation 3 delta subunit
CD4 Cluster of differentiation 4
CD44 Cluster of differentiation 44
CDK4 Cyclin-dependent kinase 4
CDK6 Cyclin-dependent kinase 6
CDKN2A Cyclin-dependent kinase inhibitor 2A
CEP cTerminally encoded peptide
CMF Cyclophosphamide/Methotrexate/Fluorouracil
CNAs Copy number alterations
cT-stage Clinical tumor stage
CXCL9 Chemokine (C-X-C motif) ligand 9
CXCR3 C-X-C motif chemokine receptor 3
DCN DECORIN
DDIT4 DNA-damage-inducible transcript 4
DFS Disease-free survival
DLDA-30 30 probe diagonal linear discriminant analysis
DRFI Distant recurrence-free interval
DRFS Distant relapse-free survival
DSBs Double strand breaks
DUSP4 Dual specificity phosphatase 4
EFS Event-free survival
EGFR Epidermal growth factor receptor
EMT Epithelial-to-mesenchymal transition
ER Estrogen receptor
ERBB2 Erb-B2 Receptor Tyrosine Kinase 2
ERK Extracellular signal-regulated kinase
ESR1 Estrogen receptor alpha
ESR2 Estrogen receptor 2
FLT3 Fms-related receptor tyrosine kinase 3
FOXO3a Forkhead box O3
GATA3 GATA binding protein 3
GBX2 Gastrulation brain homeobox 2
GFR Growth factor receptor
GGI Genomic grade index
HER2 Human epidermal growth factor receptor type 2
HOPX HOP homeobox
HR Hormone receptor
ICI Immune checkpoint inhibition
IGF1R Insulin-like growth factor 1 receptor
IHC Immunohistochemistry
IM Immunomodulatory
IntClust Integrative cluster
IT-TIL Intratumor-tumor infiltrating lymphocytes
JAK2 Janus kinase 2
Ki67 Antigen Ki67
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT16 Keratin 16
LABC Locally advanced breast cancer
LAR Luminal androgen receptor
LDHB Lactate dehydrogenase B
LOX Lysyl oxidase
M Mesenchymal
MAPK Mitogen-activated protein kinase
MCL1 Myeloid cell leukemia 1
MEK Mitogen-activated protein kinase kinase
MES Mesenchymal subtype
MKi67 Marker of proliferation Ki-67
MMP28 Matrix metallopeptidase 28
MSL Mesenchymal stem-like
mTOR Mechanistic target of rapamycin kinase
MUC1 Mucin 1, cell surface associated
MYC Master regulator of cell cycle entry and proliferative metabolism
NAC Neoadjuvant chemotherapy
OR Odds ratio
OS Overall survival
PAM50 Prediction analysis of microarray 50 subtypes
PARP Poly ADP-ribose polymerase
PARPi PARP inhibitor
PAWR Pro-apoptotic WT1 regulator
pCR Pathological complete response
PD-1 Programmed D-1
PD-L1 Programmed D ligase-1
PDGF Platelet-derived growth factor
PI Prognostic index
PI3K Phosphatidylinositol 3-kinase
PI3KCA Phosphatidylinositol 3-kinase catalytic subunit alpha
PLAU Plasminogen activator, urokinase
POLR1C RNA polymerase I And III Subunit C
PR Progesterone receptor
PTEN Phosphatase and tensin homolog
QCCs Quiescent cancer cells
RB1 Retinoblastoma protein 1
RCB Residual cancer burden
RD Residual disease
RFS Relapse-free survival
RhoA Ras homolog family member A
RPCB Residual proliferative cancer burden
SMAD4 SMAD family member 4
SNAI1 Snail family transcriptional repressor 1
SNAI2 Snail family transcriptional repressor 2
SOX9 SRY-box transcription factor 9
SPAG5 Sperm-associated antigen 5
SPARC Secreted protein acidic and cysteine-rich
SSBs Single strand breaks
STAT Signal transducer and activator of transcription
STAT1 Signal transducer and activator of transcription 1
STAT3 Signal transducer and activator of transcription 3
Str-TIL Stromal-tumor infiltrating lymphocytes
TCGA The Cancer Genome Atlas
TGFa Transforming growth factor alpha
TGFb Transforming growth factor beta
TILs Tumor infiltrating lymphocytes
TN Triple negative
TOP2A Topoisomerase IIA
TP53 Tumor protein 53
TRAR Trastuzumab risk model signature
TWIST Twist basic helix-loop-helix transcription factor
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT11 Wnt family member 11
WNT5A Wnt family member 5A