Table 1.
Antifouling effectiveness versus toxicity of compounds toward the anti-settlement of mussel plantigrades.
| Compound | EC50 (µM; µg.mL−1) | LC50 (µM) | LC50/EC50 |
|---|---|---|---|
| 4 | 21.48 (95% CI: 15.37–30.79); 4.55 | >500 | >23.28 |
| 5 | 15.46 (95% CI: 10.29–23.30); 3.52 | >500 | >32.34 |
| 7 | 11.53 (95% CI: 7.01–18.39); 2.63 | >500 | >43.37 |
| 10 | 4.60 (95% CI: 3.21–6.20); 1.36 | >500 | >108.70 |
| 15 | 28.60 (95% CI: 19.58–43.97); 12.40 | >500 | >17.48 |
| 17 | 3.53 (95% CI: 1.29–6.47); 1.25 | >500 | >141.64 |
EC50, minimum concentration that inhibited 50% of larval settlement; LC50 the median lethal dose; LC50/EC50, therapeutic ratio. Note: reference values for EC50 < 25 µg.mL−1 (U.S. Navy program) and therapeutic ratio (LC50/EC50) higher than 15.